Measured, Not Marketed
Each ingredient in Nivora, traced to peer-reviewed science. These studies evaluate the ingredients and their category, not Nivora's formula specifically. Click any study to read it yourself.
Molecules heavier than 500 Daltons cannot pass through the skin barrier, the same threshold used to develop medicine that absorbs through skin.
Bos JD, Meinardi MM. Experimental Dermatology, 2000.
View study →A meta-analysis of 25 years of clinical trials on botanical skincare found no substantial evidence of lasting improvement in age-related skin markers.
Cheng F, Feng J, et al. Journal of Cosmetic Dermatology, 2024.
View study →Topical hyaluronic acid decreased wrinkle depth by up to 40%, improved skin hydration by up to 96%, and enhanced firmness and elasticity by up to 55%.
Efficacy of a New Topical Nano-Hyaluronic Acid in Humans. J Drugs Dermatol. 33 women, avg. age 45, 8 weeks.
View study →Topical adenosine produced statistically significant improvements in wrinkle depth, dermal density, elasticity, and hydration.
Kang S, et al. International Journal of Cosmetic Science, 2018. (See also Abella ML, Int J Cosmet Sci, 2006.)
View study →5% niacinamide significantly reduced fine lines, wrinkles, hyperpigmentation, red blotchiness and sallowness, and improved elasticity.
Bissett DL, et al. Niacinamide: A B Vitamin that Improves Aging Facial Skin Appearance. Dermatologic Surgery, 2005. 50 women, 5%, 12 weeks.
View study →A topical nitric-oxide-generating serum significantly improved wrinkles, pores, evenness, pigmentation and skin vasculature over 12 weeks.
Nitric Oxide Generating Formulation as an Innovative Approach to Topical Skin Care. Cosmetics (MDPI), 2021. (See also J Drugs Dermatol, 2023: 21% lines/wrinkles, 27% texture at 12 weeks.)
View study →Centella asiatica's actives, madecassoside and asiaticoside, stimulate collagen synthesis and support skin elasticity, firmness, and barrier recovery.
Pharmacological Effects of Centella asiatica on Skin Diseases: Evidence and Possible Mechanisms. PMC, 2021.
View study →Ceramide-containing formulations significantly improve skin water content and reduce transepidermal water loss, restoring barrier function.
Kono T, et al. Clinical significance of the water retention and barrier function-improving capabilities of ceramide-containing formulations. The Journal of Dermatology, 2021.
View study →Topical panthenol significantly improves skin hydration and strengthens the skin barrier, with a significant reduction in water loss versus control.
A new topical panthenol-containing emollient: results from two randomized controlled studies. 2016.
View study →Topical vitamin C produced clinically visible and statistically significant improvement in wrinkling over 12 weeks, with biopsy-confirmed increases in collagen.
Fitzpatrick RE, Rostan EF. Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage. Dermatologic Surgery, 2002.
View study →After 8 weeks, topical beta-glucan produced a significant reduction in wrinkle depth, height, and overall skin roughness.
Pillai R, et al. Anti-Wrinkle Therapy: New Findings in the Cosmetic Treatment of Wrinkles with Beta-Glucan. Int. J. Cosmetic Science, 2005 (27 subjects). Reviewed in Food Science & Nutrition, 2025.
View study →The studies referenced above evaluate the individual ingredients and their ingredient category, not Nivora's finished formula. They are provided for educational transparency. Individual results vary. These statements have not been evaluated by the FDA, and Nivora is not intended to diagnose, treat, cure, or prevent any disease.